Single cell metabolomics

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Author(s) Heinemann, Matthias, Zenobi, Renato
Publication Type Journal Items, Publication Status: Published
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Title Single cell metabolomics
Author(s) Heinemann, Matthias
Zenobi, Renato
Journal or Series Title Current opinion in biotechnology
Issue Number 1
Start Page 26
End Page 31
ISSN 0958-1669
Publisher Elsevier
Publication Place Kidlington
Publication Date 2011-02
Abstract Recent discoveries suggest that cells of a clonal population often display multiple metabolic phenotypes at the same time. Motivated by the success of mass spectrometry (MS) in the investigation of population-level metabolomics, the analytical community has initiated efforts towards MS-based single cell metabolomics to investigate metabolic phenomena that are buried under the population average. Here, we review the current approaches and illustrate their advantages and disadvantages. Because of significant advances in the field, different technologies are now at the verge of generating data that are useful for exploring and investigating metabolic heterogeneity.
DOI 10.1016/j.copbio.2010.09.008
Additional Notes Available online 9 October 2010
Document Type Article
Publication Status Published
Language English
Assigned Organisational Unit(s) 03430
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NEBIS System Number 000579248
Source Database ID FORM-1296102956
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  author = "Heinemann, Matthias and Zenobi, Renato",
  title = "{S}ingle cell metabolomics",
  journal = "Current opinion in biotechnology",
  year = 2011,
  number = "1",
  pages = "26--31",
  month = feb,

E-Citations record created: Thu, 27 Jan 2011, 04:35:59 CET