Facile analysis of metabolites by capillary electrophoresis coupled to matrix-assisted laser desorption/ionization mass spectrometry using target plates with polysilazane nanocoating and grooves

Metadata Label Value
Author(s) Amantonico, Andrea, Urban, Pawel L., Zenobi, Renato
Publication Type Journal Items, Publication Status: Published
Full Text Search SFX for a Full-Text version of this document
Import to Mendeley Log in to provide feedback

Detailed Information

Metadata Field Content
Title Facile analysis of metabolites by capillary electrophoresis coupled to matrix-assisted laser desorption/ionization mass spectrometry using target plates with polysilazane nanocoating and grooves
Author(s) Amantonico, Andrea
Urban, Pawel L.
Zenobi, Renato
Journal or Series Title The analyst
Volume Number 134
Issue Number 8
Start Page 1536
End Page 1540
ISSN 0003-2654
1364-5528
Publisher The Royal Society of Chemistry
Publication Place Cambridge
Publication Date 2009
Abstract We present an inexpensive method and apparatus for the deposition of analytes separated by capillary electrophoresis (CE) onto a custom-designed matrix-assisted laser desorption/ionization (MALDI) target plate. This dedicated CE-MALDI plate is coated with an omniphobic polysilazane nanocoating and has an array of parallel grooves acting as recipients of the separation effluent. The 3-D pattern in the top layer of the coated plate greatly improves loading of the matrix solution prior to separation and facilitates deposition of the separated species. We demonstrate application of this straightforward protocol to the analysis of metabolites from the central metabolic pathway in a complex biological sample spiked with small molecule standards.
DOI 10.1039/b907039g
Additional Notes Received 7 April 2009, Accepted 13 May 2009, Published online 27 May 2009
Document Type Article
Publication Status Published
Language English
Assigned Organisational Unit(s) 03430
Organisational Unit(s)
NEBIS System Number 000023536
Source Database ID PP-49382
WOS-000268131500003
Description File Name MIME Type Size
No details could be found
There are no links available for this record.
This record has not been viewed during this period

@article{mntnc2009,
  author = "Amantonico, Andrea and Urban, Pawel L. and Zenobi, Renato",
  title = "{F}acile analysis of metabolites by capillary electrophoresis coupled to matrix-assisted laser desorption/ionization mass spectrometry using target plates with polysilazane nanocoating and grooves",
  journal = "The analyst",
  year = 2009,
  volume = "134",
  number = "8",
  pages = "1536--1540",
}


E-Citations record created: Fri, 02 Apr 2010, 03:46:23 CET