Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry

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Author(s) Gülbakan, Basri, Barylyuk, Konstantin, Zenobi, Renato
Publication Type Journal Items, Publication Status: Published
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Title Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry
Author(s) Gülbakan, Basri
Barylyuk, Konstantin
Zenobi, Renato
Journal or Series Title Current opinion in biotechnology
Volume Number 31
Start Page 65
End Page 72
ISSN 0958-1669
1879-0429
Publisher Elsevier
Publication Place Kidlington
Publication Date 2015-02
Abstract Over the past two decades, mass spectrometry (MS) has transformed the life sciences. The advances in understanding biomolecule structure and function by MS is progressing at an accelerated pace. MS has also largely been applied to study thermodynamic and kinetic structure of biomolecules. Herein, we highlight the recent discussions about native mass spectrometry and studies about determining stable gas phase structures, hydrogen/deuterium exchange studies about reaction kinetics and determination of binding constants of biomolecules with their ligands.
DOI 10.1016/j.copbio.2014.08.003
Document Type Article
Publication Status Published
Language English
Assigned Organisational Unit(s) 03430
Organisational Unit(s)
NEBIS System Number 000579248
Source Database ID FORM-1417708310
SCOPUS-84906761614
WOS-000348960200010
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@article{Glbkn2015,
  author = "G{\"{u}}lbakan, Basri and Barylyuk, Konstantin and Zenobi, Renato",
  title = "{D}etermination of thermodynamic and kinetic properties of biomolecules by mass spectrometry",
  journal = "Current opinion in biotechnology",
  year = 2015,
  volume = "31",
  pages = "65--72",
  month = feb,
}


E-Citations record created: Thu, 04 Dec 2014, 15:52:03 CET