Neutral desorption sampling of living objects for rapid analysis by extractive electrospray ionization mass spectrometry

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Author(s) Chen, Huanwen, Yang, Shuiping, Wortmann, Arno, Zenobi, Renato
Publication Type Journal Items, Publication Status: Published
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Title Neutral desorption sampling of living objects for rapid analysis by extractive electrospray ionization mass spectrometry
Author(s) Chen, Huanwen
Yang, Shuiping
Wortmann, Arno
Zenobi, Renato
Journal or Series Title Angewandte Chemie. International edition
Volume Number 46
Issue Number 40
Start Page 7591
End Page 7594
ISSN 1433-7851
0570-0833
1521-3773
Publisher Wiley-VCH
Publication Place Weinheim
Publication Date 2007
Keyword(s) biological samples
high-throughput screening
mass spectrometry
metabolomics
neutral desorption sampling
Abstract MS comes to life: A novel method to sample surfaces of biological objects uses a neutral gas beam for in vivo EESI mass spectrometric analysis without sample pretreatment (see picture; QTOF=quadropole time-of-flight). The sampling process results in rapid in vivo analyses with reduced ion suppression and without chemical contamination. This strategy can be used in food quality monitoring, homeland security, metabolomics, and clinical diagnosis.
DOI 10.1002/anie.200702200
Additional Notes Received 18 May 2007, Revised 24 July 2007, Published Online 4 September 2007
Document Type Article
Publication Status Published
Language English
Assigned Organisational Unit(s) 03430
Organisational Unit(s)
NEBIS System Number 000033716
Source Database ID PP-34152
WOS-000250249300009
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@article{Chn2007,
  author = "Chen, Huanwen and Yang, Shuiping and Wortmann, Arno and Zenobi, Renato",
  title = "{N}eutral desorption sampling of living objects for rapid analysis by extractive electrospray ionization mass spectrometry",
  journal = "Angewandte Chemie. International edition",
  year = 2007,
  volume = "46",
  number = "40",
  pages = "7591--7594",
}


E-Citations record created: Thu, 01 Apr 2010, 18:35:08 CET